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HISTONE DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF
专利权人:
Ralph Mazitschek
发明人:
Ralph Mazitschek,James E. Bradner,Melissa Grachan Harman
申请号:
US13985149
公开号:
US20140107166A1
申请日:
2012.02.13
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides novel compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of a compound of the invention to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.
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