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Pharmaceutical Composition Comprising a Cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
专利权人:
APEPTICO FORSCHUNG UND ENTWICKLUNG GMBH
发明人:
Hendrik Fischer,Helmut Pietschmann,Susan Jane Tzotzos,Bernhard Fischer,Rudolf Lucas
申请号:
US14784903
公开号:
US20160143266A1
申请日:
2014.04.18
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A method of conditioning/improving lung functions extracorporeally by treatment of a lung ex vivo with a cyclized compound of the amino acid sequence of formulaX1-GQRETPEGAEAKPWY-X2  Iwherein X1 comprises an amino acid (sequence) with 1 to 4 members, comprising natural or unnatural amino acids, and X2 comprises one amino acid, selected from natural amino acids; and a pharmaceutical composition, comprising a peptide of formula I as defined in any one of claims 1 to 7, in a form, which is appropriate for spraying to obtain an aerosol for inhalation, or which is appropriate for the preparation of a spray to obtain an aerosol upon spraying, which is appropriate for inhalation.
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