Medical devices for implantation in a body vessel are provided. A medical devicecan include a support member enclosing an antimicrobial coating defining a drainagelumen extending through the support member. The antimicrobial coating preferablyincludes a metal alloy comprising beryllium, nickel, copper, cobalt and/orsilicon. The metal alloy is desirably embedded in a porous biostable material,such as an ethylvinylacetate copolymer, configured to retain oxides of the antimicrobialmaterial while being sufficiently porous to permit fluid in the drainage lumento penetrate the antimicrobial coating. The medical device may be configured,for example, as a biliary or pancreatic stent.
