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Biomarker predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
专利权人:
NOVARTIS AG
发明人:
FEUERBACH DOMINIK,GOMEZ-MANCILLA BALTAZAR,HE YUNSHENG,LOPEZ-LOPEZ CRISTINA,JOHNS DONALD,MCALLISTER KEVIN HALL,PEZOUS NICOLE,SANDFORD LISA,WEISS MARKUS
申请号:
NZ70906713
公开号:
NZ709067A
申请日:
2013.12.09
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
The invention provides methods for predicting therapeutic responsiveness of a subject suffering from cognitive impairments or dysfunctions, psychotic and/or neurodegenerative disorders to treatment with (R)-3-(6-p-tolyl-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, wherein responsiveness is predicted on the basis of the individual having at least one indicative SNP of the human cytochrome P450 1A2 (CYP1A2).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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