FEUERBACH DOMINIK,GOMEZ-MANCILLA BALTAZAR,HE YUNSHENG,LOPEZ-LOPEZ CRISTINA,JOHNS DONALD,MCALLISTER KEVIN HALL,PEZOUS NICOLE,SANDFORD LISA,WEISS MARKUS
申请号:
NZ70906713
公开号:
NZ709067A
申请日:
2013.12.09
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
The invention provides methods for predicting therapeutic responsiveness of a subject suffering from cognitive impairments or dysfunctions, psychotic and/or neurodegenerative disorders to treatment with (R)-3-(6-p-tolyl-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, wherein responsiveness is predicted on the basis of the individual having at least one indicative SNP of the human cytochrome P450 1A2 (CYP1A2).