Bisykliske [3.0.1]heteroarylamider som type 1 glysin transport inhibitorer

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专利权人:

Pfizer Products Inc

发明人:

Lowe III, John Adams,Michardy, Stanton Furst

申请号：

NO20074993

公开号：

NO339422B1

申请日:

2007.10.03

申请国别(地区):

NO

年份:

2016

代理人:

摘要：

The present invention relates to a series of substituted bicyclic[3.1.0]heteroaryl amides of the Formula I, wherein A, Q, X, Y, Z and R<；SUB>；1<；/SUB>；-R<；SUB>；5 <；/SUB>；groups are defined as in the specification, that exhibit activity as glycine transport inhibitors, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their use for the enhancement of cognition and the treatment of the positive and negative symptoms of schizophrenia and other psychoses in mammals, including humans.

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