Vendeville, Sandrine Marie Helene,Last, Stefaan Julien,Demin, Samuël Dominique,Grosse, Sandrine Céline,Haché, Geerwin Yvonne Paul,Hu, Lili,Pieters, Serge Maria Aloysius,Rombouts, Geert,Vandyck, Koen,V
申请号:
HRP20191901
公开号:
HRP20191901T1
申请日:
2019.10.21
申请国别(地区):
HR
年份:
2020
代理人:
摘要:
Inhibitors of HBV replication of Formula (I-A)including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R<;sup>;a<;/sup>;to R<;sup>;d<;/sup>;, and R<;sup>;1<;/sup>;to R<;sup>;8<;/sup>;have the meaning as defined herein.The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.