The present invention provides the methods for the treatment of cancer, deliver the co-application strategy for being combined and being optionally further combined with local application immunotherapeutic agent such as cancer vaccine or NKT agonist jointly using by the part of therapeutic agent and intracellular penetration reinforcing agent. The present invention also provides the methods for using intracellular penetration reinforcing agent treating cancer with what. Method of the invention is intended to substantially kill and/or destroys target tumour cell and be transferred to those of body other parts cancer cell.本發明提供了治療癌症的方法,其使用將治療劑和細胞內滲透增强劑的局部共同遞送相組合並且任選地進一步與局部施用免疫治療劑例如癌症疫苗或NKT激動劑相組合的共施用策略。本發明還提供了用於使用細胞內滲透增强劑治療癌症的方法。本發明的方法旨在基本上殺傷和/或破壞靶腫瘤細胞以及已經轉移至身體其他部分的那些癌細胞。