FRASER, CHRISTOPHER,KISHIMOTO, TAKASHI, KEI,MALDONADO, ROBERTO, A.
申请号:
EP12776063
公开号:
EP2701705A4
申请日:
2012.04.27
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen-specific CD8+ regulatory T cells.