Disclosed are a greenhouse environment regulation method, device and a smart greenhouse. The greenhouse environment regulation method comprises: acquiring air temperature information and relative humidity information of the greenhouse environment (S101) calculating a saturation water vapor pressure difference in the current greenhouse environment by using the air temperature information and the relative humidity information (S102) determining whether the saturation water vapor pressure difference is within a preset suitable range (S103) if so, determining the current greenhouse environment as a suitable environment (S104) and if not, performing a corresponding regulation operation according to the saturation water vapor pressure difference and the preset suitable range (S105). This manner of regulating a greenhouse by calculating the saturation water vapor pressure difference can take two environmental factors including temperature and humidity into account at the same time, thereby being more comprehensive than existing technology. Further, the mechanism of transpiration in crops is also taken into consideration and is used to create more beneficial environmental conditions for the growth of the crops, thus achieving high yield and high quality, and facilitating the accurate and automated control of the greenhouse environment.Linvention porte sur un procédé de régulation dun environnement sous serre, sur un dispositif et sur une serre intelligente. Le procédé de régulation dun environnement sous serre consiste : à acquérir des informations sur la température de lair et sur lhumidité relative de lenvironnement sous serre (S101) à calculer une différence de pression de vapeur deau de saturation dans lenvironnement sous serre actuel à laide des informations sur la température de lair et des informations sur lhumidité relative (S102) à déterminer si la différence de pression de vapeur deau de saturation se situe dans une plage appropriée prédéfinie (S103) si tel est le