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FLUORO SUBSTITUTED PYRIMIDINE COMPOUNDS AS JAK3 INHIBITORS
专利权人:
Richard John Harrison
发明人:
Richard John Harrison,Andrew Hobson,Nigel Ramsden
申请号:
US13264385
公开号:
US20120040955A1
申请日:
2010.04.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to compounds of formula (I)wherein AA, R2 to R7 and X1 to X3 have the meaning as cited in the description and the claims. Said compounds are useful as selective inhibitors of JAK3 over JAK2 for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.
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