Philipp Hadwiger;Kallanthottathil G. Rajeev;Antonin De Fougerolles;Maria Frank-Kamenetsky;Muthiah Manoharan
发明人:
Antonin De Fougerolles,Maria Frank-Kamenetsky,Muthiah Manoharan,Kallanthottathil G. Rajeev,Philipp Hadwiger
申请号:
US13043228
公开号:
US08293719B2
申请日:
2011.03.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The features of the present invention relate to compounds, compositions and methods useful for modulating the expression of vascular endothelial growth factor (VEGF), such as by the mechanism of RNA interference (RNAi). The compounds and compositions include iRNA agents that can be unmodified or chemically-modified.