Compositions and methods for reduction of allograft recognition and rejection

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专利权人:

Nant Holdings IP; LLC

发明人:

Kayvan Niazi,Shahrooz Rabizadeh,Patrick Soon-Shiong

申请号：

US15682977

公开号：

US10344280B1

申请日:

2017.08.22

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Allograft recognition and rejection of donor cells in a host is reduced by limiting or even abrogating expression of the donor cell's MHC-I peptides to avoid CD8+ T-cell recognition and by expression of inhibitory factors to avoid an NK cell mediated cytotoxic response.

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中国工程科技知识中心

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http://www.ckcest.cn/home/