Varian Medical Systems International AG;The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel
发明人:
Christopher Barry Locke,Santtu Ollila,Karl Kenneth Bush
申请号:
US16235211
公开号:
US20200101320A1
申请日:
2018.12.28
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.