The present invention provides apparatus and method for imaging a subject in clinical examination. An apparatus for imaging a subject, comprising: a plurality of light sources (20) for illuminating a region of interest within the subject, at least a portion of the light sources (20) being divided into groups and being actuated group by group, each actuated group of the light sources (20) providing an illumination flash with a predetermined duration, and different groups of the light sources (20) illuminating the region of interest at different angles； and a light detector (40) for receiving light reflected by the subject to form a frame of image for the region of interest per imaging period of the light detector (40), and the predetermined duration of the illumination flash being shorter than the imaging period, enough to enable different groups of the light sources to illuminate the region of interest per imaging period at different times within the imaging period. According to the apparatus, glint in images of the region of interest is reduced in real-time.
