A machine for ozone-therapy blood treatment having an extracorporeal circuit (1) comprising a filter (9), designed to produce a plasma component from the blood of a patient (P), an arterial line (3), designed for transport of the blood from the patient (P) to the filter (9), a venous line (4), designed for transport of the blood from the filter (9) to the patient (P), a reaction chamber (11), in which the plasma component is made to react with a gas containing ozone, a delivery line (12), designed for transport of the plasma component from the filter (9) to the reaction chamber (11), a return line (13), designed for transport of the plasma component that has reacted with the ozone from the reaction chamber (11) to the venous line (4), and an assembly for preparation and movement of the ozone (14), designed for the production of the ozone and its inlet into the reaction chamber (11).
