Subhrangsu S. Mandal,Khairul I. Ansari,James D. Grant, III
申请号：
US12491103
公开号：
US08198322B2
申请日:
2009.06.24
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention describes the synthesis and biochemical activities of metallo-salen compounds and their derivatives. The Mn(III)-salen and Fe(III)-salen derivatives of the present invention are potential anti-tumor agents, that affect cell viability, induce strong apoptotic activity, cause nuclear condensation, fragmentation, and ultimately death in breast cancer cells MCF-7.
