БИГЭ Томас Дж. (US),ДЖОНСТОН Син (US),МОЛНАР Деннис П. (US),ТАНАКА Кен С. (US),ЭРБЕЙТ Роберт Д. (US)
申请号：
RU2010140682/15
公开号：
RU2010140682A
申请日:
2009.03.05
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A method of treating a patient for infection, comprising administering to said patient an effective amount of 9 - [(2,2-dimethyl-propylamino) methyl] minocycline or a salt thereof sufficient to treat said patient, said infection being selected from the group consisting of methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant Staphylococcus aureus (MRSA), B-streptococcus, green streptococcus, Enterococcus, and combinations thereof. ! 2. The method according to claim 1, wherein said salt is a hydrochloric acid salt. ! 3. The method according to claim 1 or 2, wherein said patient is a human. ! 4. The method according to claim 1 or 2, wherein said 9 - [(2,2-dimethyl-propylamino) methyl] -minocycline or its salt is administered orally. ! 5. The method according to claim 1 or 2, wherein said 9 - [(2,2-dimethyl-propylamino) methyl] minocycline or its salt is administered intravenously. ! 6. The method according to claim 1 or 2, in which the specified 9 - [(2,2-dimethyl-propylamino) methyl] -minocycline or its salt is administered orally at a dose of from about 100 mg to about 300 mg per day. ! 7. The method according to claim 6, in which the specified 9 - [(2,2-dimethyl-propylamino) methyl] -minocycline or its salt is administered orally at a dose of approximately 200 mg per day. ! 8. The method according to claim 1 or 2, in which the specified 9 - [(2,2-dimethyl-propylamino) methyl] -minocycline or its salt is administered intravenously at a dose of from about 50 mg to about 150 mg per day. ! 9. The method of claim 8, wherein said 9 - [(2,2-dimethyl-propylamino) methyl] minocycline or its salt is administered intravenously at a dose of about 100 mg per day. ! 10. A pharmaceutical composition for oral administration containing from about 100 to about 300 mg of 9 - [(2,2-dimethyl-propylamino) methyl] minocycline or a salt thereof and a pharmaceutical1. Способ лечения пациента от инфекции, включающий введение указанному пациенту эффективного количества
