Douglas G. McFadden,Eric C. Bartee,Christopher R. Cogle
申请号：
US14124800
公开号：
US20140328804A1
申请日:
2012.06.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A method of treating or preventing graft versus host disease (GVHD) in a subject receiving a graft comprising hematopoietic cells is provided. The method comprises contacting the graft ex vivo with an amount of a Myxoma Virus effective to inhibit proliferation of T lymphocytes in the graft and to treat or prevent GVHD in the host subject following infusion of the graft into the subject. After the contacting of the graft with the Myxoma Virus, the method comprises transplanting the virus-treated graft into the subject.
