ALEXION PHARMACEUTICAL;ALEXION PHARMACEUTICALS; INC.
发明人:
ORTIZ, STEPHAN,GENTILE, JILLIAN,PHILOMINATHAN, LEENA,ROUTHIER, ERIC,MASON, BRUCE
申请号：
CA3069756
公开号：
CA3069756A1
申请日:
2018.07.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure relates to stable aqueous solutions comprising a high concentration of an anti-C5 antibody (e.g., ravulizumab) and methods for preparing the solutions. The disclosure also provides methods for treating or preventing complement-associated disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), using the solutions. Also featured were therapeutic kits containing one or more of the solutions and a means for administering the solutions to a patient in need such a treatment.
