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테트라펩타이드 및 이를 함유하는 피부노화 방지 및 항염효능의 화장료 조성물
专利权人:
MIWON COMMERCIAL CO.; LTD.
发明人:
LEE, Yunsub,이윤섭,CHOI, Hyejung,최혜정,KIM, Myeongok,김명옥
申请号:
KRKR2013/001498
公开号:
WO2013/137569A1
申请日:
2013.02.25
申请国别(地区):
WO
年份:
2013
代理人:
摘要:
The present invention relates to a tetrapeptide represented by the following chemical formulas 1 and 2, and a skin antiaging, skin wrinkle alleviating and anti-inflammatory cosmetic composition containing the same as an active ingredient. According to the present invention, the tetrapeptide alleviates wrinkles by inhibiting the generation of MMPs, which are collagenase, and suppresses inflammation, and thus provides a cosmetic material having excellent wrinkle and inflammation alleviation. Particularly, the wrinkle alleviating and anti-inflammatory tetrapeptide can be used by being added to various basic cosmetic compositions in the form of a toner, a lotion, a cream, a foundation, an essence, a gel, a pack, a foam cleanser, a body oil, a lip stick, a mascara, a makeup base, a soap, or the like, does not irritate the skin, and is remarkably safe for the skin.[Chemical formula 1]R-R1-Gly-Leu-Phe[Chemical formula 2]R-Gly-Leu-Phe-R2(In chemical formulas 1 and 2, R is H, a C1-C18 acyl group, or an alkenyl group having at least one double bond, Leu can be D-Leu or L-Leu, and Phe can be D-Phe or L-Phe. In addition, a moiety represented by R1 and R2 in chemical formulas 1 and 2 can be selected from amino acids, particularly, 20 natural amino acids and phenylglycine, which is an unnatural amino acid, and the C terminal can be in the form of a carboxylic acid or an amide.)La présente invention concerne un tétrapeptide représenté par les formules chimiques suivantes 1 et 2 ainsi quune composition cosmétique contre le vieillissement et linflammation de la peau qui en comprend en tant quingrédient actif. Selon la présente invention, le tétrapeptide permet de réduire les rides par inhibition de la production de MMP (métalloprotéinases matricielles), qui sont des collagénases tout en supprimant linflammation, Elle procure ainsi un matériau cosmétique présentant dexcellentes qualités pour latténuation des rides et de linflammation. En particulier, les qualités antirides et anti-in
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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