This creation relates to an ampoule break safety sheath, which is used for breaking the ampoule. The ampoule includes a head section and a bottle body. The safety sheath comprises: a body, which includes a front material and a back material, and the front material and the back material are common. A sheath space is formed for the head section to be inserted. After the head section is inserted into the sheath space, the user can break the head section from the bottle body by using the safety sheath.本創作關於一種安瓿折斷安全護套,係用於安瓿的折斷,該安瓿包含頭段與瓶身,該安全護套包含:本體,其包含前面材與後面材,該前面材與該後面材共同形成護套空間供該頭段置入,其中當該頭段置入該護套空間後,使用者可經由使用該安全護套而將該頭段從該瓶身折斷。