ALONSO FERNANDEZ, María José,TEIJEIRO OSORIO, Desireé,TEIJEIRO VALIÑO, Carmen María,CADETE PIRES, Ana
申请号：
AU2018361481
公开号：
AU2018361481A1
申请日:
2018.11.02
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
The present invention generally relates to particles, including nanocapsules or other nanoentities, comprising a polymer such as polysialic acid. The particles are able to access the interior of the cells, and/or to procure the intracellular release of the associated drugs. In 5 one aspect, the present invention is directed to nanocapsules or other entities having an exterior or surface comprising a polymer such as polysialic acid. In some cases, targeting moieties such as Lyp-1 or tLyp-1 peptide are bonded to the polymer, e.g., using aminoalkyl (C
