One embodiment provides an instrument (100) including an infusion sleeve (102), aspiration tube (108), and infusion /aspiration tip (104). The sleeve can include a body defining an infusion channel (103). The tube can be in the infusion channel and define an aspiration channel (105). The tip can conform to the distal end of the tube. The tip can .seal a gap between the sleeve and tube and can include a flange (114) with a profile (e.g., a tapered portion) corresponding to the profile of the sleeve. The sleeve and tip can be keyed such that the sleeve directs fluid in one direction and the tip draws fluid perpendicularly from that direction. The tips aspiration channel can extend distally beyond its aspiration port (110). The tip can extend to a point adjacent to an infusion port (106) of the sleeve. A disposable component (including an aspiration tube and infusion/aspiration tip) for use with instruments is provided.
