Systems and methods for manually filling a prescription order. A manual fill device may be incorporated into a manual fill center of a pharmacy operated by one or more pharmacists and/or pharmacist technicians to manually fill certain prescription containers. The manual fill device may include a control unit which may operate at the direction of the order processing device. The manual fill device may also include a distribution section automating distribution of containers for manual fulfillment, and a manual section in which a pharmacist may utilize available pharmaceuticals to manually fill orders.