Inhibitors of protein kinases

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专利权人:

Princeton Drug Discovery Inc

发明人:

Kan He,Lining Cai

申请号：

US15516355

公开号：

US09890163B2

申请日:

2016.10.11

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Protein kinases are regulators of cellular signaling and their functional dysregulation is common in carcinogenesis and many other disease states or disorders. The present invention relates to novel chemical entities that have biological activity to modulate mammalian protein kinase enzymes. In particular, compounds of the invention display potent inhibition of breast tumor related kinase (BRK).

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中国工程科技知识中心

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http://www.ckcest.cn/home/