The compounds mentioned in this list have antiviral activity, especially the activity of inhibiting the replication of respiratory virus (VSR). In addition, it mentions pharmaceutical ingredients containing these compounds and compounds used to treat respiratory tract Cindy virus infections. 1. Claim 1: a formula compound (1),Including any stereoform related to chemical isomerization, including any stereoform related to chemical isomerization, wherein a is a compound of formula (2) or (3)；N is 0, 1 or 2, M is 1 or 2, x1,X2 and X3 select X1 as CR1, X2 as CR1, X3 as CR1,O X1 is n, X2 is CR1, X3 is CR1,Or X1 is CR1, X2 is n, X3 is CR1,O X1 is cr11, X2 is CR1, X3 is n, or X1 is n and X2 is CR1, X3 is n, where each R1 is selected independently of the group composed of hydrogen, halogenation, hydrogen Xi, c8318331832424；C8321XI-83318324248A1.C8321XI-833124；-C8321XI-83318324；e. Hydroxialquilo c83217c83318324y and hydroxialquiloxi c832883318324 were used；R1 is ch832323 or ch8322； ch832323；R2 is hydrogen, halogen or c832183383242448a；R3: halo or ch8323jo； r8308；e. Phenyl is substituted by one, two or three substitutes selected from halogen, hydroxyl, cyanogen and alkyl c831832421, respectively；1. Poly (acyl halide) c831832421；e.C8321Xi-8331832421；a. The heteromorphic or c83216c833248 was replaced by isomerization, r83099a was hydrogen, c8328331248o was water calcium oxide, c8326c83318324；The selection of each r83100s is independent of c83218c8318324244j matrix composed of hydrogen；e. Hydroxi, halo and hydrocarbon c832131；a. Each r8310；； 74919 is independent of the hydrogen and halide groups； r8311 is hydrogen, acqui c8332183318324；o hydroxieloquilo C8321E.8331832424；R831222 ES-OH，CN，O（CO）-Nr1 2 3，-C83218C8331832424-（CO）-Nr°1°3，-（CO）-Nr-r-（CS）-Nr°R1 3，-（CO）-Nrê2-CN，-（CO）-Nrê2-SO832222-R1-R83088；-No.1-（co）-R8308；-No.1-（co）-O-R-R8308；-Nr°1-SO832228-R1°83088；-NH832222，-R183099,-SO8322；R83088；-SO832222-Nr 1 3，-SO832222-Nr 2-（CO）-R1 8308；O-SO（=NH）（-R18308）；Or heterosexual； 1R2 and
