Amjad Ali,Joann Bohn,Qiaolin Deng,Zhijian Lu,Peter J. Sinclair,Gayle Taylor,Christopher Thompson,Nazia Quraishi
申请号:
US12815146
公开号:
US08193365B2
申请日:
2010.06.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1, A1 and A2 are each an aromatic ring, a 5-6-membered heterocyclic ring, an aromatic ring fused to a heterocyclic ring, a phenyl ring fused to a heterocyclic ring, or a cycloalkyl ring.