Patrick J. Treado,John S. Maier,Shona Stewart,Jeffrey Cohen,Matthew Nelson
申请号：
US13316703
公开号：
US20120150028A1
申请日:
2011.12.12
申请国别(地区):
US
年份:
2012
代理人:
摘要：
System and method for differentiating tissue margins in a biological sample using pulsed laser excitation and time-gated detection. A region containing a biological tissue is irradiated with substantially monochromatic pulsed laser light to thereby produce Raman scattered photons. The Raman scattered photons are detected using time-gated detection to thereby obtain a Raman spectroscopic image from the irradiated region characteristic of either a neoplastic portion or a non-neoplastic portion of the region containing the biological tissue. A boundary between a neoplastic portion and a non-neoplastic portion is differentiated and the boundary location in the Raman spectroscopic image is displayed.
