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COMPOSES AROMATIQUES SUBSTITUES ET UTILISATIONS PHARMACEUTIQUES DE CEUX-CI
专利权人:
PROMETIC BIOSCIENCES INC.
发明人:
ZACHARIE, BOULOS,PENNEY, CHRISTOPHER,GAGNON, LYNE,BIENVENU, JEAN-FRANCOIS,PERRON, VALERIE,GROUIX, BRIGITTE
申请号:
CA2761018
公开号:
CA2761018C
申请日:
2010.05.03
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to substituted aromatic compounds of Formula II,thepharmaceutically acceptable salts thereof, the pharmaceutical compositioncontaining them, andtheir pharmaceutical uses. More particularly, Formula Il is(See Formula II)wherein n is 1; Q is C1-C2 alkyl; R1 is straight chain C5 alkyl, C6 alkyl, C5-C6 alkenyl, or C5-C6alkynyl; R2 is H, halogen, haloalkyl, ORb, SRb, or NRcRd;R3 is H, halogen,haloalkyl, straightchain C1-C4 alkyl, ORb, SRb, or NRcRd; R4 is H, halogen, haloalkyl, C1-C4alkyl, ORb, SRb, orNRcRd; R5 is H or ORb; Rb is H; and Rc and Rd are independently chosen from: Hor C1-C4alkyl. Particular aspects of the invention relate to the use of thosecompounds in the preventionand/or treatment of various diseases and conditions in subjects, including theprevention ortreatment of (i) blood disorders, (ii) renal disorders, a nephropathies, orrenal disordercomplications; (iii) inflammatory-related diseases; and/or (iv) oxidativestress related disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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