甲基巴多索隆的2，2-二氟丙酰胺衍生物、其多晶型物及使用方法

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专利权人:

REATA PHARMACEUTICALS INC.

发明人:

ANDERSON, ERIC,DECKER, ANDREA,LIU, XIAOFENG

申请号：

HK15107525.2

公开号：

HK1207085A

申请日:

2015.08.05

申请国别(地区):

HK

年份:

2016

代理人:

摘要：

The present invention relates to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-l,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide and polymorphic forms and pharmaceutical compositions thereof for use in the treatment of cancer in combination with immunotherapy, for use in the treatment of conditions associated with oxidative stree caused by mitochondrial dysfunction and for use in the treatment of seizure disorders.

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