GRÖPPEL, Manfred,VITT, Daniel,KOHLHOF, Hella,MÜHLER, Andreas
申请号:
AU2018371177
公开号:
AU2018371177A1
申请日:
2018.11.22
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention refers to a 2-({3-fluoro-3'-methoxy-[1,1'-biphenyl]-4- yl}carbamoyl)cyclopent-1-ene-1-carboxylic acid) according to formula (I) and a novel dosage regimen as well as their uses in the treatment of chronic inflammatory and/or autoimmune diseases. The said compound of formula (I) inhibits dihydroorotate dehydrogenase (DHODH), and is known for the treatment and prevention of diseases, in particular their use in diseases where there is an advantage in inhibiting dihydroorotate dehydrogenase (DHODH).