Tamper-resistant dosage form for oxidation-sensitive opioids

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专利权人:

Grunenthal GmbH

发明人:

Bartholomaus, Johannes,Geissler, Anja,Bertram, Ulrike,Griessmann, Kornelia

申请号：

AU2010275754

公开号：

AU2010275754B2

申请日:

2010.07.21

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising - an opioid (A), - - a free physiologically acceptable acid (B) in an amount of from 0T001 to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form, and - a polyalkylene oxide (C) having a weight average molecular weight M

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