LNCARN POUR LA THÉRAPIE ET LE DIAGNOSTIC DE L'HYPERTROPHIE CARDIAQUE

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专利权人:

Medizinische Hochschule Hannover

发明人:

申请号：

EP15717502.7

公开号：

EP3134526B1

申请日:

2015.04.22

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention relates to a pharmaceutical composition comprising (i) a compound promoting the expression and/or the activity of one or more long noncoding RNAs (IncRNAs) selected from SEQ ID NOs 12, 8 to 11 and 13； and/or (ii) a compound inhibiting the expression and/or the activity of one or more IncRNAs selected from SEQ ID NOs 1 to 7, 27 and 28. The present invention also relates to a compound (i) promoting the expression and/or the activity of one or more IncRNAs selected from SEQ ID NOs 12, 8 to 11 and 13； and/or (ii) inhibiting the expression and/or the activity of one or more IncRNAs selected from SEQ ID NOs 1 to 7, 27 and 28 for use in treating or preventing cardiac hypertrophy.

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