Four branched dendrimer-PEG for conjugation to proteins and peptides

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专利权人:

José Ángel Ramón Hernández

发明人:

José Ángel Ramón Hernández,Fidel Raúl Castro Odio,Vivian-María Sáez Martinez,Rolando Páez Meircles,Eduardo Fernández Sánchez

申请号：

US12095335

公开号：

US08703893B2

申请日:

2006.11.20

申请国别(地区):

US

年份:

2014

代理人:

摘要：

A polymeric dendrimer-like structure with four branches of monomethoxy-polyethylene glycol that can be represented as:The carboxylic group of the previous structure can be functionalized for the production of conjugates of pharmaceutical interest. The binding of this dendrimer-like polyethylene glycol to therapeutic proteins improves their in vitro and in vivo stability.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/