Laura Bronsart,Christopher Contag,Christian Stokes
申请号：
US14210551
公开号：
US20140271485A1
申请日:
2014.03.14
申请国别(地区):
US
年份:
2014
代理人:
摘要：
There is a need for a broadly applicable, strain non-specific, bioluminescent imaging tool that will enable researchers to study a β-cell mass in the context of development, disease or transplantation. The disclosure, therefore, encompasses embodiments of a method of identifying a non-diabetic pancreatic β-cell, the method comprising the steps of: delivering to a pancreatic β-cell a composition comprising a coelenterazine allowing the β-cell to generate a coelenterazine-dependent bioluminescent signal and identifying the cell as a non-diabetic pancreatic β-cell by detecting the emitted coelenterazine-dependent bioluminescent signal.
