An autoinjector includes a body (10 12) a syringe carrier (34) supporting a syringe (13) or cartridge with a needle at its forward end for movement from a rearward position to a forward position to extend a needle the syringe or cartridge having a barrel of generally cylindrical form having at a forward region thereof a forward facing abutment surface wherein the syringe carrier is provided with a retention surface arranged to cooperate with said forward facing abutment surface on the syringe to prevent or limit forward movement of the syringe relative to the syringe carrier the autoinjector further including a removable needle shield (15) releasably attached to said syringe or cartridge and shrouding the needle a cap (14) attached to the forward end of said body and forwardly removable said cap having a removal surface (120) for engaging said needle shield whereby removal of said cap removes said needle shield.
