In one aspect, solvent systems are described herein. In some embodiments, such a solvent system comprises a disaccharide component, choline halide or choline acetate, and water. The water is present in the solvent system in an amount of 5 weight percent to less than 25 weight percent, and the solvent system is free of crystals. In another aspect, biomolecular compositions are described herein. Such a composition can comprise one or more biological molecules dissolved in a solvent system described herein. In yet another aspect, methods of storing a biological composition are described herein. In some instances, such a method comprises contacting the biological composition with a liquid preservative composition, wherein the liquid preservative composition comprises a solvent system or biomolecular composition described herein.
