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Methods for treating and preventing neutrophil-derived net toxicity and thrombosis
专利权人:
Kimberly Martinod;Grace M. Thomas;Simon De Meyer;Alexander Brill;Denisa D. Wagner;Tobias A. Fuchs
发明人:
Denisa D. Wagner,Tobias A. Fuchs,Simon De Meyer,Kimberly Martinod,Alexander Brill,Grace M. Thomas
申请号:
US14119499
公开号:
US09642822B2
申请日:
2012.05.25
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Embodiments of the technology described herein are based upon the discoveries that neturophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
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