Provided is a sterilization apparatus capable of reliably measuring a pressure difference between a pressure in a sterilization tank and an atmospheric pressure using an absolute pressure sensor. In a sterilization apparatus using a gas in which steam, gas, or other gas is used as a sterilizing agent, a door (31) for opening and closing an opening is provided, and a sterilization tank (32) containing an object to be sterilized therein; A first sensor 50 for measuring the pressure of the air as an absolute pressure, a second sensor 60 for measuring the atmospheric pressure as an absolute pressure, a pressure value in the sterilization tank 32 measured by the first sensor 50, and a second A control unit 58 which receives the atmospheric pressure value measured by the sensor 60, compares the input sterilization tank pressure value with the input atmospheric pressure value, and calculates a pressure difference between the sterilization tank internal pressure and the atmospheric pressure. Have. [Selection diagram] Fig. 1【課題】絶対圧センサを用いて、滅菌槽内の圧力と大気圧の圧力差を確実に測定できる滅菌装置を提供する。【解決手段】滅菌剤として蒸気、ガスその他の気体が用いられる気体による滅菌装置30において、開口部を開閉する扉31が設けられ内部に被滅菌物を収容する滅菌槽32と、滅菌槽32内の圧力を絶対圧で測定する第1のセンサ50と、大気圧を絶対圧で測定する第2のセンサ60と、第1のセンサ50で測定された滅菌槽32内圧力値と、第2のセンサ60で測定された大気圧値とが入力され、入力された滅菌槽内圧力値と大気圧値とを比較して滅菌槽内圧と大気圧との圧力差を算出する制御部58と、を具備する。【選択図】図1