ÉPONGE DE GÉLATINE CONTENANT UNE SOLUTION DE TAMPON DE PHOSPHATE (PBS) OU UN TAMPON DE PHOSPHATE ET APPLIQUÉE À UNE CHIMIO-EMBOLISATION ARTÉRIELLE TRANSCATHÉTER, ET SON PROCÉDÉ DE PRÉPARATION
HJMEDICAL CO., LTD.;주식회사 에이치제이메디칼; LTD.;주식회사 엔스메디칼;NTH MEDICAL CO., LTD.;HJMEDICAL CO.
发明人:
SON, Jiu,손지우
申请号：
KRKR2014/012414
公开号：
WO2016/093412A1
申请日:
2014.12.16
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a gelatin sponge containing a phosphate buffer solution (PBS) or phosphate buffer and applied to transcatheter arterial chemoembolization, and a method for preparing the same and, more specifically, to a gelatin sponge containing a phosphate buffer solution (PBS) or phosphate buffer and applied to transcatheter arterial chemoembolization, and a method for preparing the same, wherein the method comprising: a step of immersing a gelatin sponge in a phosphate buffer solution (PBS) or phosphate buffer at 4-37°C for 3-12 hours； a step of freeze-drying the gelatin sponge, which is impregnated with the phosphate buffer solution (PBS) or phosphate buffer, at a temperature condition of -10°C to -35°C for 30 minutes to 16 hours； a step of pulverizing the freeze-dried gelatin sponge； a step of separating the pulverized gelatin sponge into sizes of 10-100 μm, 100-300 μm, 300-500 μm, and 500-700 μm, respectively, wherein, after the pulverized gelatin sponge is transferred to a hospital while being kept in disinfected vials, or in package containers in which the pulverized gelatin sponge is stored in any one of a phosphate buffer solution and a phosphate buffer, the pulverized gelatin sponge is bound to physiological saline, distilled water, and an anticancer agent, which are introduced thereto, to be used as a therapeutic agent for liver cancer.La présente invention concerne une éponge de gélatine contenant une solution de tampon de phosphate (PBS) ou un tampon de phosphate et appliquée à une chimio-embolisation artérielle transcathéter, et son procédé de préparation et, plus spécifiquement, une éponge de gélatine contenant une solution de tampon de phosphate (PBS) ou un tampon de phosphate et appliquée à une chimio-embolisation artérielle transcathéter, et son procédé de préparation, le procédé comprenant : une étape consistant à immerger une éponge de gélatine dans une solution de tampon de phosphate (PBS) ou un tampon de phosphate à 4-37 °C pe
