Klinikum rechts der Isar der Technischen Universität München
发明人:
申请号:
EP14706057.8
公开号:
EP2958587B1
申请日:
2014.02.25
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
In a first aspect, the present invention relates to use 9 agonists of TLR and/or 4 agonists of TLR in preventative or therapeutic vaccine. According to this vaccination strategies, 9 agonists of TLR and/or 4 agonists of TLR, which are suitable for or designed to be used as, jumps immunocyte expansion multiplied by agent is jumped to enhance the vaccination strategies of mainly jumping of CD8 T cells in quantity and function. In particular, 9 agonists of TLR and/or 4 agonists of TLR are used as component, individual to be administered is vaccinated after the priming. Vaccination strategies are particularly useful, and have anti-acute and chronic infection intracellular pathogens or anti-tumor vaccine. In another aspect, the present invention relates to a kind of components of external member to contain Primary proxy people and the multiplication jump agent present invention.