Provided herein are methods for detecting and/or confirming the neurogenesis effect of cholesterol, at least one oxysterol, EPA, EGCG and/or resveratrol utilizing adipose-derived stem cells (ADSCs). Further provided are methods of promoting neurogenesis in ADSCs. Also provided are methods for the use of cholesterol, an oxysterol, EPA, EGCG and/or resveratrol for the production of a neurologic component that may be incorporated into a nutritional composition for promoting neurogenesis in a pediatric subject.本發明提供用於檢測及/或確認用於脂肪幹細胞(ADSC)之膽固醇、至少一種氧固醇(oxysterol)、EPA、EGCG及/或白藜蘆醇的神經新生效果之方法。本發明進一步提供促進脂肪幹細胞神經新生之方法。本發明亦提供使用膽固醇、氧固醇、EPA、EGCG及/或白藜蘆醇來製造可被納入用於促進兒科個體之神經新生的營養組成物中之神經學組分的方法。