Composés de pyrazole-amines utilés en tant qu'inhibiteurs de kinase

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

申请号：

EP11005867.4

公开号：

EP2385041B1

申请日:

2004.05.03

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates to compounds having the formula, and pharmaceutically-acceptable salts, prodrugs, solvates, isomers, and/or hydrates thereof, wherein Q is an optionally-substituted phenyl, pyridyl, pyridazinyl, pyrimidinyl, or pyrazinyl ring； R 2 is alkyl or an amino group as defined herein； and Z is optionally-substituted oxadiazolyl. The compounds are surprisingly advantageous in preparing medicaments for treating p38 kinase related conditions and/or in preparing medicaments for use in treating inflammatory disorders or conditions in a patient.

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