International Publication Date (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 1111111101111011101010111110101111101110101111110110010111011111101111011111 International Bureau .. .... ..Yejd ..... ...„1 (10) International Publication Number WO 2017/173321 Al 5 October 2017 (05.10.2017) IN I PO I P CT (51) (21) (22) (25) (26) (30) (71) (72) (74) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 38/17 (2006.01) CO7K 16/30 (2006.01) kind of national protection available): AE, AG, AL, AM, A61K 39/00 (2006.01) CO7K 4/12 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, C07K 14/47 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FL GB, GD, GE, GH, GM, GT, International Application Number: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, PCT/US2017/025462 KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, International Filing Date: M
