The University Court of the University of Aberdeen;ApaTech Limited
发明人:
Iain R. Gibson,Janet M.S. Skakle,Daniel J. Hadden,Thomas Buckland
申请号:
US14274014
公开号:
US20140348943A1
申请日:
2014.05.09
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a process for the preparation of a silicate and carbonate co-substituted calcium phosphate material. The process comprises the steps of: forming a silicon and optionally carbon-containing calcium phosphate precipitate by an aqueous precipitation method involving preparing an aqueous solution comprising phosphate ions, silicate ions, calcium ions and optionally carbonate ions, wherein the ratio of Ca/P and of Ca/(P+Si) in the solution is maintained above approximately 1.67; and heating the precipitate in an atmosphere comprising carbon and oxygen to form a silicate and carbonate co-substituted calcium phosphate material.The present invention also provides a synthetic carbonate and silicate co-substituted hydroxyapatite material, as well as a biomedical material.