The present invention relates to a nucleic acid molecule comprising a double stranded structure, whereby the double stranded structure is a first stretch (stretch) of the (contiguous) nucleotides comprising a first strand and a second strand, the first strand is adjacent and include also the first stretch is at least partially complementary to a target nucleic acid, yet the second strand wherein the addition comprises a second stretch of contiguous nucleotides second stretch is at least partially complementary, and in the first stretch the first stretch is SEQ ID NO: 1 to the nucleotide core sequence or a part of a nucleic acid sequence according to (NM_013355) comprises an at least partially complementary nucleic acid sequences, wherein the nucleotide core sequence and then the nucleotide sequence Nucleotide positions 482 to 500 of SEQ ID NO: 1 (SEQ ID NO: 2) Nucleotide position 1555 to 1573 of SEQ ID NO: 1 (SEQ ID NO: 4) Nucleotide position 1556 to 1574 of SEQ ID NO: 1 (SEQ ID NO: 6) Nucleotide position 1559 to 1577 of SEQ ID NO: 1 (SEQ ID NO: 8) Nucleotide position 1566 to 1584 of SEQ ID NO: 1 (SEQ ID NO: 10) Nucleotide position 2094 to 2112 of SEQ ID NO: 1 (SEQ ID NO: 12) Nucleotide position 2102 to 2120 of SEQ ID NO: 1 (SEQ ID NO: 14) Nucleotide position 2286 to 2304 of SEQ ID NO: 1 (SEQ ID NO: 16) Nucleotide position 2761 to 2779 of SEQ ID NO: 1 (SEQ ID NO: 18) Sequence of nucleotide positions No. 1 2763 to 2781 (SEQ ID NO: 20) Nucleotide position 2764 to 2782 of SEQ ID NO: 1 (SEQ ID NO: 22) Sequence of nucleotide positions No. 1 2843 to 2861 (SEQ ID NO: 24) Nucleotide position 2844 to 2862 of SEQ ID NO: 1 (SEQ ID NO: 26) or Nucleotide position 2846 to 2864 of SEQ ID NO: 1 comprises a (SEQ ID NO: 28), Preferably, the core nucleotide sequence, and then the nucleotide sequence Nucleotide position 1555 to 1573 of SEQ ID NO: 1 (SEQ ID NO: 4) Nucleotide position 1556 to 1574 (SEQ ID NO: 6) Nucleotide position 1559 to 1577 of SEQ ID NO: 1 (SEQ ID
