IMMUNOCONJUGUES D'HAPTENE POLYPEPTIDIQUE MIMETIQUE DE GHRELINE AYANT UNE SOLUBILITE ET UNE IMMUNOGENEICITE AMELIOREES ET LEURS PROCEDES D'UTILISATION

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专利权人:

THE SCRIPPS RESEARCH INSTITUTE

发明人:

JANDA, KIM D.,MAYOROV, ALEXANDER V.

申请号：

CA2826853

公开号：

CA2826853A1

申请日:

2012.02.09

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Immunoconjugates for impeding weight gain and treating obesity in a subject are disclosed. The immunoconjugates comprise a ghrelin mimetic polypeptide hapten, a spacer moiety comprising one of more polyethylene glycol (PEG) units, and a protein carrier moiety. Immunoconjugates optionally include a conjugation moiety for conjugating the polypeptide hapten with a linker moiety or the protein carrier moiety and a linker moiety for conjugating the conjugation moiety with the protein carrier moiety.

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