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HYBRID FORMULATION OF RESPONSIVE POLYMERIC NANOCARRIERS FOR THERAPEUTIC AND DIAGNOSTIC DELIVERY
专利权人:
University of Delaware
发明人:
Chad Greco,Thomas Epps, III,Millicent Sullivan
申请号:
US16316375
公开号:
US20200181649A1
申请日:
2017.07.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a nanocomplex comprising at least one agent and a nanocarrier. The agent is bound to the nanocarrier. The nanocarrier comprises at least one cationic polymer responsive to a stimulus, at least one anionic polymer and at least one lipid. The agent is capable of being released from the nanocarrier upon exposure to the stimulus. The released agent is active. The nanocomplex may be used to deliver the agent into cells, in which the agent may be released from the nanocarrier upon exposure of the cells to the stimulus.
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