#$%^&*AU2010200822B220131010.pdf#####ABSTRACT The present invention is related to use of protein kinase N beta or a fragment or derivative thereof as a downstream target of the PI 3-kinase pathway, preferably as a downstream drug target of the PI 3-kinase pathway.1/13 -o ecc 0. U, a. ca) E E CZ 0)0 04t E o 0 EE L. a, ___ 10C oN " s opou qdwu(i jo *wsnIOAW I ID 0 Go. 0 C30 .2m. C? 00. XN L. u C4 0 S E x *EjIL E 09C 1.