Improved processes for preparing ticagrelor intermediate, 4,6-dichloro-5-nitro-2-(propylthio)pyrimidine

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专利权人:

Actavis Group PTC EHF

发明人:

Khile, Anil Shahaji,Patel, Jayesh,Trivedi, Nikhil,Pradhan, Nitin Sharadchandra

申请号：

AU2011216991

公开号：

AU2011216991A1

申请日:

2011.02.15

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

Provided herein are improved, commercially viable and industrially advantageous processes for the preparation of a substantially pure ticagrelor intermediate, 4,6-dichloro-5-nitro-2- (propylthio)pyrimidine, Formula (II). The intermediate is useful for preparing ticagrelor, or a pharmaceutically acceptable salt thereof, in high yield and purity.

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